VIDYASAGAR UNIVERSITY FACULTY INFORMATION SYSTEM

Self Declared Document

Name Dr. Sagar Acharya Designation Assistant Professor Department Name ZOOLOGY Office Phone No +91 3222 298-289 / Centrex Extn. 289 Email ID sacharya@mail.vidyasagar.ac.in Fax 03222-275329 Mobile No 9830427756 Personal Website Address Department of Zoology, Vidyasagar University, Midnapore, West Bengal, India. Pin-721 102

Educational Qualification Degree Name Institute Year of passing/awarded PhD University of Calcutta, Place of Work: IPGME&R, Kolkata and Calcutta School of Tropical Medicine 2010 M.Sc. University of Calcutta 2003 B.Sc. University of Calcutta 2001 Title of the Ph. D. Thesis Studying the Expression of Pivotal Proteins Playing Central Role in the Cell Survival and Cell Death Cascades in Experimental Brain Tumor Model with and without T11TS

Career Profile / Teaching Experience Assistant Professor at Vidyasagar University since 18th April 2012-till date Guest Lecturer at Postgraduate Dept. of Zoology of Maulana Azad College, Kolkata since 2009-2012 ICMR Centenary Postdoctoral Fellow at National Institute of Cholera & Enteric Diseases (NICED) since 2010-17th April 2012 Senior Research Fellow (CSIR-NET) at Calcutta School of Tropical Medicine, Kolkata since 2008-2010 Senior Research Fellow (CSIR-NET) at IPGME &R, Kolkata since 2007-2008 Junior Research Fellow (CSIR-NET) at IPGME &R, Kolkata since 2005-2007 Research Fellow at IPGME &R, Kolkata since 2004-2005

Specialization/Research Area Field of Specialization Research Area/ Areas of Interest Genetics Molecular Biology Immunology Cancer Immunotherapy Inflammation

Course/ Subject Taught Cell Biology Biochemistry Human genetics Bio-Statistics Genetics and Molecular Biology (Special Paper) Immunology

Conference/ Symposium /Journal Paper / Books Published International Publication Title Published in Published on Published by Role Details A longitudinal study on the prevalence of iron deficiency anemia in the multiethnic communities of Jhargram, West Bengal. Acta Biologica Szegediensis Feb, 2023 University of Szeged Corresponding Author Impact Factor: 0.70000 Indexing: SCOPUS Article's Web Link: Therapeutic intervention of glioma with the novel antineoplastic agent T11TS: the story so far. Immunotherapy Aug, 2022 Future Medicine First Author,Co-Author Impact Factor: 4.04000 Indexing: SCOPUS Article's Web Link: Impact of hyperglycemia on the expression of GLUT1 during oral carcinogenesis in rats Molecular Biology Reports Jun, 2022 Springer Co-Author Impact Factor: 2.74000 Indexing: SCOPUS Article's Web Link: Akt phosphorylation orchestrates T11TS mediated cell cycle arrest in glioma cells Cancer Investigation 2021 Tailor and Francis First Author Impact Factor: 2.17600 Indexing: SCOPUS, ESCI, SCI, SCIE, SSCI, AHCI, UGC CARE Article's Web Link: A review on SARS-CoV2 drug regimens inferring plausible mechanisms to impede the viral propagation and cytokine storm Int J Community Med Public Health. 8(4):2061-2069 2021 International Community Of Medicine and Public Health, Medip Academy   Impact Factor: Indexing: Article's Web Link: Genetic diversity and multiple antibiotic resistance index study of bacterial pathogen, Klebsiellapneumoniae strains isolated from diseased Indian major carps Folia Microbiologica; doi: 10.1007/s12223-019-00701-7 2019 Springer   Impact Factor: Indexing: Article's Web Link: Isolation, identification and characterization of Klebsiellapneumoniae from infected farmed Indian Major Carp Labeorohita (Hamilton 1822) in West Bengal, India. Aquaculture; 482 (111-116) 2018 Elsevier   Impact Factor: Indexing: Article's Web Link: T11TS inhibits glioma angiogenesis by modulation of MMPs, TIMPs, with related integrin av and TGF-ß1 expressions Tumor Biology 35 (3), 2231-2246 2014 Springer   Impact Factor: Indexing: Article's Web Link: Significant modulation of macrophages associated cytokines TNF-a, VEGF and apoptotoic protein Bax, Bcl2 abrogates tumor cells Cellular immunology 284 (1), 172-181 2013 Elsevier   Impact Factor: Indexing: Article's Web Link: T11TS Induced Modulation of Macrophages Associated Cytokines TNF- a,VEGF and Apoptototic Protein Bax, Bcl2 Abrogates Tumor Cells in In vitro Grade I,II Human Glioma J Clin Cell Immunology 2-9; S1: 006. doi:10.4172/2155-9899.S1-006 2013 JCCI, an open access journal   Impact Factor: Indexing: Article's Web Link: T11TS impedes glioma angiogenesis by inhibiting VEGF signaling and pro-survival PI3K/Akt/eNOS pathway with concomitant upregulation of PTEN in brain endothelial cells Journal of neuro-oncology 113 (1), 13-25 2013 Springer   Impact Factor: Indexing: Article's Web Link: Chitin-binding protein GbpA of Vibrio cholerae induces interleukin-8 gene expression in intestinal cells through a TLR2/TLR1/CD14 complex The FASEB Journal 26, 1156.5 2012 FASEB   Impact Factor: Indexing: Article's Web Link: Immunomodulatory role of TIITS in respect to cytotoxic lymphocytes in four grades of human glioma. Cellular Immunology 276: 176–186. 2012 Elsevier   Impact Factor: Indexing: Article's Web Link: Comparative evaluation of T11 target structure and its deglycosylated derivative nullifies the importance of glycan moieties in immunotherapeutic efficacy. Acta Biochim Biophys Sin (Shanghai) 44(3):259-68. 2012 ABBS & Institute of Biochemistry and Cell Biology (SIBS, CAS).   Impact Factor: Indexing: Article's Web Link: Therapeutic Profile of T11TS vs. T11TS+MiADMSA: A Hunt for a More Effective Therapeutic Regimen for Arsenic Exposure Asian Pacific J Cancer Prev, 13, 2943-2948 2012 Asian Pacific Organization for Cancer Prevention and The UICC-Asian Regional Office and An Official Journal of The International Association of Cancer Registries   Impact Factor: Indexing: Article's Web Link: T11TS exerts effector function by activating immune cells in CNS against glioma where cytokine modulation provide the favourable microenvironment to act. Ind J Exp Biol 48: 879-888. 2010 NISCAIR   Impact Factor: Indexing: Article's Web Link: Arsenic induced carcinogenesis: an immunological approach. Asian Pacific Journal of Cancer Prevention 11(2): 479-90. 2010 Asian Pacific Organization for Cancer Prevention and The UICC-Asian Regional Office and An Official Journal of The International Association of Cancer Registries   Impact Factor: Indexing: Article's Web Link: Induction of G1 arrest in glioma cells by T11TS is associated with up-regulation of Cip1/Kip1 and concurrent downregulation of cyclin D (1&3). Anti Cancer Drugs; 21: 53–64. 2010 Wolters Kluwer and Lippincott Williams & Wilkins   Impact Factor: Indexing: Article's Web Link: Bax and Bid act in synergy to bring about T11TS mediated glioma apoptosis via the release of mitochondrial Cytochrome c and subsequent caspase activation. International Immunology; 2 (12): 1489–1505. 2008 Oxford University Press & Japanese Society for Immunology   Impact Factor: Indexing: Article's Web Link: Acute toxicity studies of T11TS: a glycopeptide with antineoplastic effects against glioma. Toxicology International; 14(1) 47-56. 2007 The Society of Toxicology   Impact Factor: Indexing: Article's Web Link: The Other Side of the Coin: Beneficiary Effect of ‘Oxidative Burst’ Upsurge with T11TS Facilitates the Elimination of Glioma Cells Cellular and Molecular Biology 53(5), 53-62. 2007 Published by C.M.B. Association,FRANCE   Impact Factor: Indexing: Article's Web Link: T11TS/SLFA-3 Differentially Regulate The Population Of Microglia And Brain Infiltrating Lymphocytes To Reduce Glioma By Modulating Intrinsic Bcl-2 Expression Rather Than p53. Central Nervous System Agents in Medicinal Chemistry. 7, 145-155. 2007 Bentham Science Publishers   Impact Factor: Indexing: Article's Web Link: A sequential scanning of the immune efficiency in Astrocytoma (Grade I-Grade III), Meningioma & Secondary glioma patients with and without therapeutic scheduling Cancer Investigation, 24(5):502-513 2006 Informa Healthcare London, UK   Impact Factor: Indexing: Article's Web Link: National Publication Title Published in Published on Published by Role Details Subacute toxicity study of T11TS: A Nove immunotherapeutic glycopeptide against glioma. Advances in Pharmacology & Toxicology. 11 (1): 1-10. 2010 Connect-Journals (CJ)   Impact Factor: Indexing: Article's Web Link: Differential functional modulation of the death proteins in in vivo and in vitro microenvironments in experimental brain tumors (glioma) Journal of Cell & Tissue Research; 8(1):1211-1224. 2008 CTR Publications   Impact Factor: Indexing: Article's Web Link: A Novel Adjuvant Immunotherapeutic Approach In Treating Canine Pyoderma Adv. Life Sc. 1(1): 9-19. 2008 IJALS   Impact Factor: Indexing: Article's Web Link: Functional and receptor modulations of T lymphocytes and macrophage in acute and subacute dose finding studies of a novel immunotherapeutic molecule T11TS. Journal of Cell & Tissue Research 7(2):1013-1018. 2007 CTR Publications   Impact Factor: Indexing: Article's Web Link: Other Publication Book Published Title of the Book Published by Published on Role Details Biodiversity in Vidyasagar University Campus: A Pictorial Atlas Vidyasagar University Publication Division 2019 Author & Editor Indexing: Link: Book Chapter Published

Ph. D. Thesis Guidence Ongoing / Submitted Ph. D. Thesis Scholar Name Thesis Title Co Supervisor Status Complete in Year Moumi Mandal Prevalence of anemia in association with single nucleotide polymorphism of iron related genes among multiethnic groups of Jhargram district of West Bengal   Submitted   Subhamita Dalal Assessment of hyperglycemic impact on 4NQO (tobacco equivalent chemical) induced oral carcinogenesis in Wistar rat: a molecular approach   Ongoing 0 Sanchari Bhattacharya Anti-inflammatory and anti-oxidant properties of methanolic extract of Amaranthus spinosus in murine hepatic fibrosis model   Ongoing   Niladri Prasad Mishra Deciphering viper venom-induced variations of brain endothelial tight junction protein complexes in Rattus norvegicus   Ongoing   Poulomi Chatterjee Investigating the effects of viper venom on astrocyte-pericyte-endothelial interactions at the blood brain -barrier in Rattus norvegicus.   Ongoing   Awarded Ph. D. Thesis Scholar Name Thesis Title Co Supervisor Status Complete in Year Abhishek Das Molecular identification and pathogenecity study of Klebsiella pneumonia isolated from fishes of West Bengal Dr. BK Behera Awarded

Project Work Ongoing Project Works Project title Worked as Funding Agency Amount in Rs. Duration in years Period Year to Year Status Investigating the effects of microglial miRNAs in modulating blood-brain barrier microenvironment throughout glioma progression Principal Investigator ICMR 3759680 3 year 2023 2026 Exptd. Ongoing Investigating the viper venom-induced alterations in blood-brain barrier in the murine model Principal Investigator SERB 2832170 3 year 2023 2026 Exptd. Ongoing Investigating the astrocyte-pericyte-endothelial crosstalk to maintain blood-brain-barrier homeostasis in Indian viper-envenomed model Principal Investigator CSIR 1800000 3 year 2023 2026 Exptd. Ongoing Completed Project Works Project title Worked as Funding Agency Amount in Rs. Duration in years Period Year to Year Status Assessment of Serum cytokine levels with special emphasis to iron metabolism of the anemic population of Jungalmahal area of Midnapore Principal Investigator UGC, Innovative Program (Science) 440000 2 year 2016 2018 Completed Delineating signal cascades induced by colonization factor of Enterotoxigenic E. coli Principal Investigator UGC 600000 2 year 2014 2016 Completed

Membership of Learned Society  Indian Science Congress

Conference /Seminar/Workshop Attended/Organised Conference /Seminar/Workshop Attended Title of the Seminar/Conference/Workshop Year Role Held at and Organiser Continuing Medical Education (CME) cum Workshop on Stem Cell Therapy and Research 2011 Attended Netaji Subhas Chandra Bose Cancer Research Institute, Kolkata. National Conference on Interface of Science & Environment: Emerging Public Health Challenges, SCIENVIRON 2011 Attended 13th Annual Meeting of Society of Science & Environment. Kolkata 5th World Congress of Cellular and Molecular Biology organized by World Society Cellular and Molecular Biology, France 2009 Paper Presenter World Society Cellular and Molecular Biology, France in collaboration with Dept. of Biotechnology. Devi Ahilya University, Indore International conference on Integrative Physiology: Modern Perspective 2009 Paper Presenter Physilogical Society of India, Kolkata New frontiers in Scientific Meet on Heamatology and oncology 2009 Attended Netaji Subhas Chandra Bose Cancer Research Institute, Kolkata Workshop on “Bioinformatics in Genomics & Proteomics 2008 Attended IIT, Kharagpur Indian Academy of Neurosciences, Kolkata Chapter 2007 Paper Presenter S.N.Pradhan Centre foe Neurosciences, University of Calcutta 34th Annual Conference of the Indian Immunology Society 2007 Poster Presentation Indian Immunology Society, National AIDS Research Institute, Pune New frontiers in Scientific Meet on Heamatology and oncology 2007 Paper Presenter Netaji Subhas Chandra Bose Cancer Research Institute, Kolkata National Seminar on Dimension in Zoological Research in Human Welfare 2007 Paper Presenter Department of Zoology, University of Calcutta & The Zoological Society, Kolkata The XVIII Annual Conference of The Physiological Society of India 2006 Paper Presenter Department of Physiology, Presidency College, Kolkata Brain Tumors - WFNS - World Federation of Neurosurgical Societies, Kolkata chapter 2006 Attended National Neuroscience Centre, Kolkata Conference /Seminar/Workshop Organised

Awards Award Name Awarded By Year ICMR Centenary Postdoctoral Fellowship Indian Council of Medical Research, Govt. of India 2010 CSIR-NET-JRF in LIFE SCIENCES CSIR-UGC, Govt. of India 2004 NET - Lectureship in Life Sciences CSIR-UGC, Govt. of India 2004 NET - Lectureship in Life Sciences CSIR-UGC, Govt. of India 2003 National Scholarship Scheme Govt. of India 2001

Disclaimer : The information on this website has been prepared with the greatest possible care and the aim is to keep all information up-to-date. The University cannot gurantee the correctness, completeness, topicality or quality of the information presented. In the event of doubt concerning the content of the website, please contact the relevant faculty.